|Year : 2021 | Volume
| Issue : 1 | Page : 63-66
Intra-articular osteoid osteoma of tempromandibular joint: A rare entity
Uday Kiran Uppada1, Ramen Sinha1, BS Ravi Kiran1, M Susmitha1, Syeda Afroz Ahmed2
1 Department of Oral and Maxillofacial Surgery, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India
2 Department of Oral and Maxillofacial Pathology, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India
|Date of Submission||17-Mar-2020|
|Date of Decision||01-Jan-2021|
|Date of Acceptance||10-Feb-2021|
|Date of Web Publication||19-May-2021|
Dr. Uday Kiran Uppada
Department Oral and Maxillofacial Surgery, Sri Sai College of Dental Surgery, Vikarabad, Telangana
Source of Support: None, Conflict of Interest: None
Osteoid osteomas are benign neoplasms of bone that generally manifests in the long bones. Intra-articular osteoid stoma of tempromandibular joint is a rare manifestation. We report a rare case of osteoid osteoma of the mandibular condyle encompassing the intra-articular space with emphasis on how to differentiate it from other benign neoplasms of the bone that affects the jaws.
Keywords: Neoplasm, osteoma, TMJ
|How to cite this article:|
Uppada UK, Sinha R, Ravi Kiran B S, Susmitha M, Ahmed SA. Intra-articular osteoid osteoma of tempromandibular joint: A rare entity. J NTR Univ Health Sci 2021;10:63-6
|How to cite this URL:|
Uppada UK, Sinha R, Ravi Kiran B S, Susmitha M, Ahmed SA. Intra-articular osteoid osteoma of tempromandibular joint: A rare entity. J NTR Univ Health Sci [serial online] 2021 [cited 2021 Dec 6];10:63-6. Available from: https://www.jdrntruhs.org/text.asp?2021/10/1/63/316323
| Introduction|| |
Osteoid osteoma is a benign, solitary neoplasm of bone. It is the third most common benign bone tumor. The incidence of this neoplasm accounts to 10% of all benign bone tumors. It has a male predilection and is most commonly seen in the second decade of life. Osteoid osteomas occur generally in the long bones predominantly the femur. They have a limited growth potential and are estimated to reach a maximum size of 1.5–2 cm. Osteoid osteoma can ensue in any part of the skeleton. However, only a few cases have been stated in the craniofacial region, displaying a marked predilection for the mandible. We report a rare case of osteoid osteoma of the mandibular condyle encompassing the intra-articular space.
| Case Presentation|| |
A 27-year-old female reported to our department with pain and clicking sound in her left jaw in addition to difficulty in mouth opening since 1 year. She gave a history of domestic violence 1 year back after which she had pain and clicking in her left jaw on opening and closing of mouth. She used medication for pain relief. Due to difficulty in eating and pain on opening of mouth 3 months later, she reported to a nearby hospital for treatment. Based on the history and the clinical presentation, a provisional diagnosis of left condylar fracture was made and intermaxillary fixation was advised. However, she refused for the treatment.
Patient reported to our unit presently complaining of pain in her left jaw in addition to difficulty in mouth opening. She gives a history that the pain did not subside on medication. Clinical examination revealed no scars over the mid-face on left side and there was no obvious facial asymmetry. Palpation of the preauricular region revealed restricted condylar movements on left side, and a bony hard, non-tender swelling in the left preauricular region. Mouth opening was inadequate in addition to this; the mandible deviated to the opposite side on maximal mouth opening. Orthopantomogram revealed a well circumscribed, uniformly radiopaque, round mass on left TMJ region occupying space of the condyle. A thin irregular joint space can be appreciated within the substance of the mass in antero-posterior direction as shown in [Figure 1]. Radiographic interpretation of CBCT showed a sclerosed nodule measuring approximately 1.5 × 2 cm located anatomically on the superior aspect of the left mandibular condyle as shown in [Figure 2].
A provisional diagnosis of osteoid osteoma of mandible was made and the patient was taken up for surgery under GA. Patients consents was obtained. A preauricular incision was given and the neoplasm was approached following layer wise dissection. Surgical osteotomy was carried out and the neoplasm was separated from the left mandibular condyle as shown in [Figure 3] and [Figure 4]. Surgical contouring of the residual left mandibular condyle was done and the wound was closed in layers. The pain immediately resolved after surgery and there was an improvement in mouth opening gradually. Histopathology revealed areas of mature lamellar bone with resting and reversal lines and few osteocytes within the bone. It showed anastomotic trabeculae of osteoid and woven bone lined by osteoblasts in loose fibro vascular strong and multinucleated giant cells. Foci of hematopoietic elements are surrounded by cortical bone margin with minimum fibro-fatty marrow suggestive of osteoid osteoma of the mandible as shown in [Figure 5]. On 1 year follow-up, the patient revealed adequate pain free mouth opening without any deviation. There was no recurrence as shown in [Figure 6].
|Figure 3: Intraoperative view showing the lesion superior to the condyle in the intra-articular region|
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|Figure 5: (a) 10x magnification of the histopathologic view of the lesion. (b) 40x magnification of the histopathologic view of the lesion|
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|Figure 6: Postoperative OPG showing proper TMJ architecture following removal of the intra-articular lesion|
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| Discussion|| |
The etiopathogenesis of osteoid osteoma is still indistinct. Few authors believe that the neoplasm forms when there is uninhibited growth in the bone. However, the possibility of reactive mechanism, triggered by trauma or infection has been postulated as the most common cause for osteoid osteoma., In this present case, the patient gives a history of traumatic incidents with a hard object 1 year prior to the onset of her symptoms. Hence, it can be postulated that the trauma she sustained could be a contributory factor in the pathogenesis.
Clinically, the neoplasm is characterized by severe pain that gets worse at night and can be relieved by the use of NSAIDs. Literature shows that high levels of inflammatory mediators are found in the nidus of this neoplasm revealing the characteristic nociception and rationale for the use of NSAIDs. Several studies have shown that these neoplasms are found to be less responsive to NSAIDs when they occurs in the joints compared to the extra-articular lesions.,,, This could be the reason as to why in the present case, there was no pain relief following use of medication.
Literature shows that intra-articular neoplasm manifests as a diffuse joint pain that is typically associated with swelling and tenderness of the involved area. It mimics an intra-articular derangement, resulting in a possible delayed of diagnosis., Literature also states that when the neoplasm involves the mandibular condyle it presents with trismus, limitation of mouth opening, progressive malocclusion with midline shift toward the unaffected side, contralateral mandibular deviation, and facial asymmetry.,
On plain film radiographs, they present as well-defined, densely sclerotic radio-opacities. However, it is difficult to differentiate osteomas from osteochondromas or condyle hyperplasia particularly when they involve the intra-articular region on a plain radiograph. Osteomas are difficult to differentiate from foci of condensing osteitis, focal chronic sclerosing osteomyelitis, or idiopathic osteosclerosis. Three-dimensional CT is the gold standard in assessing the dimensions of the lesion and planning the surgery. Activity in the lesion can be evaluated using scintigraphy.
Osteoid osteoma has a close resemblance to osteoblastoma. However, due to its limited growth potential, size and the anatomical areas involved, osteoid osteoma can be differentiated from osteoblastoma.,, Once an osteoid osteoma is diagnosed, patients need to be evaluated for Gardners syndrome. Surgical intervention remains the most commonly recommended treatment option for osteoid osteoma in order to restore the function and aesthetics., In the present case, a surgical excision, with a conservative removal of the lesion followed by TMJ arthroplasty was performed. Even though recurrence associated with this neoplasm is extremely rare, it is necessary to review the patient both clinically and radiographically periodically after the surgery.
| Conclusion|| |
Intra-articular osteoid osteoma of tempromandibular joint is a rare manifestation. Due to its nonspecific symptoms the diagnosis is deceptive. CT images were helpful in revealing the distinctive radiographic features and localization of the lesion. Surgical intervention for removal of the neoplasm resulted in the complete relief of symptoms and uneventful healing of the area.
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
Institutional ethical clearance taken.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Rolvien T, Zustin J, Mussawy H, Schmidt T, Pogoda P, Ueblacker P. Intra-articular osteoid osteoma as a differential diagnosis of diffuse mono-articular joint pain. BMC Musculoskelet Disord 2016;17:455S.
Allen SD, Saifuddin A. Imaging of intraarticular osteoid osteoma. Clin Radiol 2003;58:845-52.
Issa SA, Abdulnabi HA, Alshewered AS. Intra-articular osteoid osteoma of tempromandibular joint: A case report. Int J Surg Case Rep 2019;62:9-13.
Deferm JT, Steens SCA, Vriens D, Bekers EM, Kalaykova SI, Borstlap WA. Chronic temporomandibular joint pain: Two cases of osteoid osteoma and a review of the literature. Int J Oral Maxillofac Surg. 2017;46:1130-7.
An SY, Shin HI, Choi KS, Park JW, Kim YG, Benavides E, et al
. Unusual osteoid osteoma of the mandible: Report of case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol 2013;116:e134-40.
Horikawa FK, Freitas RR, Maciel FA, Gonçalves AJ. Peripheral osteoma of the maxillofacial region: A study of 10 cases. Braz J Otorhinolaryngol 2012;78:38-43.
Lee EH, Shafi M, Hui JH. Osteoid osteoma: A current review. J Pediatr Orthop 2006;26:695-700.
Goto T, Shinoda Y, Okuma T, Ogura K, Tsuda Y, Yamakawa K, et al
. Admin-istration of nonsteroidal anti-inflammatory drugs accelerates spontaneous healing of osteoid osteoma. Arch Orthop Trauma Surg 2011;131:619-25.
Tochihara S, Sato T, Yamamoto H, Asada K, Ishibashi K. Osteoid osteoma in mandibular condyle. Int J Oral Maxillofac Surg 2001;30:455-7.
Almeida LE, de Oliveira Filho MA. Giant mandibular condyle osteoma. J Craniofac Surg 2011;22:1147-9.
de Souza NT, Cavalcante RC, de Albuquerque Cavalcante MA, Hespanhol W, de Oliveira MR Jr, de Carvalho Ferreira D, et al
. An unusual osteoma in the mandibular condyle and the successful replacement of the temporomandibular joint with a custom-made prosthesis: A case report. BMC Res Notes 2017;10:727.
Mancini JCMA, Woltmann M, Felix VB, Freitas RR. Peripheral osteoma of the mandibular condyle. Int J Oral Maxillofac Surg 2005;34:92-3.
Siar CH, Jalil AA, Ram S, Ng KH. Osteoma of the condyle as the cause of limited-mouth opening: A case report. J Oral Sci 2004;46:51-3.
Misra N, Srivastava S, Bodade PR, Rastogi V. Osteoma of temporomandibular joint: A rarity. BMJ Case Rep 2013;2013:bcr 2013200268. doi: 10.1136/bcr-2013-200268.
Sayan NB, Uçok C, Karasu HA, Gunhan O. Peripheral osteoma of the oral and maxillofacial region: A study of 35 new cases. J Oral Maxillofac Surg 2002;60:1299-301.
Yalcinkaya U, Doganavsargil B, Sezak M, Kececi B, Argin M, Basdemir G, et al
. Clinical and morphological characteristics of osteoid osteoma and osteoblastoma: Retrospective single-center analysis of 204 patients. Ann Diag Pathol 2014;18:319-25.
[Figure 1], [Figure 2], [Figure 3], [Figure 4], [Figure 5], [Figure 6]